Medicinski pregled 2010 Volume 63, Issue 5-6, Pages: 324-332
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Non-atherosclerotic arteriopathy as the cause of ishemic stroke among young adults
Jovićević Mirjana, Divjak Ivana, Slankamenac Petar, Jovanović Aleksandar, Ružička Svetlana, Dickov Aleksandra
The study comprised 100 ischemic stroke patients of both sexes aged 15-45
years who were treated at the Clinic of Neurology of the Clinical Center of
Vojvodina in the period January 2001 - September 2004. All study subjects
were divided into three age groups: 15-25, 26-35 and 36-45 years. Sex, age
and risk factors for cerebrovascular disease were determined in all patients.
Diagnostic procedures applied in all patients included brain computed
tomography and/or magnetic resonance imaging, routine laboratory tests,
Doppler imaging of extra and endocranial blood vessels and coagulation tests.
Contrast and/or transesophageal echocardiography, immunological blood assays,
magnetic resonance angiography and/or computed tomography angiography and/or
conventional angiography, trombophilia markers, antiphospholipid antibodies
and toxicological examination, etc. were performed in selected patients.
Non-atherosclerotic arteriopathies were found in 8% of all study subjects,
and were the most frequent cause of stroke in the age group 15-25. Carotid
artery dissection was the most frequent diagnosis overall, found in 6% of all
patients. Fibromuscular dysplasia and systemic vasculitis were diagnosed in
one patient each. Moyamoya disease, Takayasu disease, infectious and isolated
vasculitis of the CNS were not found in our patients.
Keywords: Brain Ischemia, Stroke, Intracranial Arterial Diseases, Carotid Artery Diseases, Adolescent, Adult
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