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Journal of the Serbian Chemical Society 2004 Volume 69, Issue 11, Pages: 969-972
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Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelli var. conescens

Vajs Vlatka, Trifunović Snežana, Janaćković Peđa T., Soković Marina, Milosavljević Slobodan, Tešević Vele

Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi. The overall activity of one of them 2-hydroxy-2,6,10-trimethyl-7,10-epoxydodeca- 3,11-dien-5-on, was comparable to that of the antibiotic bifonazole.

Keywords: Artemisia lobelii All. var. conescens, Asteraceae, davanones, umbelliferone, antifungal activity