Acta chirurgica iugoslavica 2007 Volume 54, Issue 1, Pages: 63-70
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Bumbaširević V.M., Jovanović B., Palibrk I., Karamarković A.R., Radenković D., Gregorić P., Đukić V.R., Stevanović R., Simić D., Ivančević N.N.
Hemorrhagic shock is a condition produced by rapid and significant loss of blood which lead to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, organ damage and can be rapidly fatal. Despite improved understanding of the pathophysiology and significant advances in technology, it remains a serious problem associated with high morbidity and mortality. Early treatment is essential but is hampered by the fact that signs and symptoms of shock appear only after the state of shock is well establish and the compensatory mechanisms have started to fail. The primary goal is to stop the bleeding and restore the intravascular volume. This review addresses the pathophysiology and treatment of hemorrhagic shock.
Keywords: shock, hemorrhage, oxygen delivery, crystalloids, colloids, transfusion
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