doiSerbia

Mammography in detection clinically occult breast carcinoma

Golubičić I.V. (Institut za onkologiju i radiologiju Srbije, Beograd)
Pavlović T.M. (Institut za onkologiju i radiologiju Srbije, Beograd)
Borojević N. (Institut za onkologiju i radiologiju Srbije, Beograd)
Dodić R. (Institut za onkologiju i radiologiju Srbije, Beograd)
Miletić N. (Institut za onkologiju i radiologiju Srbije, Beograd)
Marković Ž. (Odeljenje radiologije, Klinički centar Srbije, Beograd)

Aim: The significance of mammography in detection of nonpalpable breast cancer Material and methods: This prospective study was conducted at the Institute for oncology and radiology of Serbia in Belgrade. It involved 198 asymptomatic women with performed screening mammography, 154 specimen mammography, out of witch 38 had stereotaxic mark, "ex tempore" biopsy, while 44 women had "ex tempore" biopsy and adequate surgery. Results: Screening mammography revealed suspect microcalcifications in 148 cases, impaired structural tissue in 59 and focal condensation in 55 cases. Histologic examination verified breast carcinoma in 80 patients with very statistical significance of ductal type, especially comedo subvariant (p<0.001). Pleomorphic microcalcifications smaller than 0.5 mm of grouped or segmented form are statistically very significant for malignity (p<0,001) as well as associated microcalcifications with altered architectony and focal tissue condensation (p<0.001). Conclusion: Mammography has great significance in detection of occult breast carcinoma which are not only preinvasive, but also microinvasive and invasive. This fact leads to the neccesity of introduction of legal obligation for mammography screening, especially for women aged between 50 and 70 years.

Keywords: screening, mammography, clinically occult breast carcinoma